Tom qab thiab Txheej txheem cej luam
Nicotine, feem ntau paub txog nicotine, yog pyridine derivative alkaloid. Nws muaj qee qhov alkalinity thiab tuaj yeem hnov mob nrog cov kua qaub los ua cov ntsev amine. Yog li ntawd, cov ntsev nicotine yog qhov tseem ceeb amine ntsev. Piv rau nicotine nws tus kheej, cov ntsev nicotine muaj ntau tsawg dua rau qhov ncauj thiab caj pas mucosa. Thaum nkag rau hauv lub cev, nicotine salts decompose rau hauv nicotine thiab cov acid sib haum. Piv rau nicotine, tib lub loj ntawm cov ntsev nicotine tau muab tsawg dua nicotine rau lub cev. Nicotine ntsev kuj tseem muaj qhov hnyav ntawm cov kua qaub. Yog li no, cov ntsev tsis tau ib txwm muaj peev xwm ntxiv rau 50mg los yog ze li ntawm 100mg, tab sis cov ntsiab lus nicotine tiag tiag yuav tsawg dua ib nrab. Nicotine ntsev nyob rau hauv e- kua yog ua nrog citric thiab tartaric acids.
Npaj Piv Txwv: Cov kauj ruam npaj ntawm nicotine ntsev (nicotine ntsev) yog li 573g ntawm cov nicotine hnyav), thiab maj mam sib tov thiab txhuam cov kua qaub kom tau txais kev daws teeb meem. (2) Do cov tshuaj sib tov ntawm 200 RPM ntawm 25℃rau 65 teev, thiab tom qab ntawd txias rau chav sov liab nicotine ntsev (nicotine ntsev). Daim ntawv thov cov roj luam yeeb hauv tshuab hluav taws xob, suav los ntawm qhov hnyav, suav 2- 10}}} seem ntawm glycerol, thiab 1-5 ntu ntawm cov roj uas tsis muaj roj. Kev tsim cov khoom e-luam yeeb ua kua suav nrog cov kauj ruam hauv qab no:
S1. Hnyav thiab npaj cov ntsev nicotine (nicotine ntsev) (5 seem), propylene glycol (80 ntu), thiab roj roj (3 seem) raws li qhov sib piv;
S2. Npaj nicotine ntsev (nicotine ntsev): Ua ntej, sib tov sorbic acid, thiab gluconic kua qaub nyob rau hauv ib tug cua sov (cua sov thiab stirring ceev ntawm 60-80 rpm). Ib txhij, preheat ascorbic acid, glycyrhizic acid, tartaric acid, thiab glycolic acid. Tom qab ntawd, ntxiv ascorbic acid, glycyrhizic acid, tartaric acid, thiab nicotine acid, thiab nicotine, hauv qhov kev txiav txim ntawd, mus rau lub taub hau kom sov. Tom qab cov tshuaj tiv thaiv txaus hauv lub tank, cov khoom siv reacted yog crushed kom tau txais nicotine ntsev.
S3. Tso qhov sib tov ntawm propylene glycol thiab glycerol hauv lub tank sib xyaw. Tom qab ntawd, tso cov nicotine ntsev tau txais hauv kauj ruam S2 hauv lub tank hlau thiab do. Txuas ntxiv nplawm thiab sib xyaw ntawm qhov kub ntawm 25-50℃rau 1-3 teev kom yaj. Tom qab ntawd, lim los ntawm lub taub lim dej (nrog lub pore loj ntawm 80-120 mesh) ntawm chav sov kom tau txais cov ntaub ntawv ntshiab.
S4. Ntxiv cov roj volatile (sib xyaw ntawm qej volatile roj thiab pob zeb qus volatile nyob rau hauv vaj huam sib luag) rau qhov filtrate, thiab thaum kawg foob thiab pob kom tiav cov khoom e-luam yeeb ua kua.