Pharmaceutical-qib nicotine ntsev compounded nrog siab -purity thermal-cov neeg ua haujlwm txias (WS series). Engineered rau siab - nicotine xa nrog tswj caj pas ua xua nyob rau hauv pod-mod thiab pov tseg systems. Muab nyob rau hauv cov kua bulk configurations rau automated filling kab, featuring standardized viscosity thiab deg nro tsis tsim los txo cov to thiab qhuav -kub txaus ntshai nyob rau hauv raug kaw ib puag ncig.
Technical Specifications
|
Nicotine Concentration Range |
20 mg / mL txog 50 mg / mL (Customizable mus txog 100 mg / mL intermediate concentrate) |
|
Nicotine Purity |
>= 99.9% (USP Monograph, luam yeeb- muab los lossis cov kev xaiv hluavtaws muaj) |
|
Base Ratio (PG/VG) |
50/50, 60/40, los yog tus neeg siv khoom- qhia txog kev cai sib piv (+/- 1% gravimetric kam rau ua) |
|
Cooling Agent Matrix |
WS-23, WS-3, los yog L-menthol (concentration adjustable ntawm 0.5% mus rau 3.0%) |
|
Cov ntsiab lus dej (Karl Fischer) |
< 0.1% |
|
Tus nqi pH |
6.5 - 7.5 (buffed rau tshuaj stability thiab coil ntev) |
|
Qhov tshwm sim |
Ntshiab, tsis muaj xim rau daj ntseg daj kua |
|
Qhov ntom |
1.18 g / cm3 rau 1.24 g / cm3 (nyob ntawm PG / VG thiab ntsev payload) |
Kev tsim qauv
Primary Salt Acids:Benzoic acid, salicylic acid, los yog customized organic acid complexes engineered los khi dawb nicotine molecules, suppressing vapor harshness ntawm elevated concentrations.
Cov kuab tshuaj:USP-qib Propylene Glycol (PG) thiab Zaub Glycerin (VG), tau los nrog cov ntaub ntawv xov xwm - ntawm - saib xyuas.
Flavour Carriers:Nruab nrab compounding puag npaj rau theem nrab tsw kev koom ua ke ntawm tus neeg siv khoom tsim khoom.
Flavour Profile
Base Profile:Ntxuav, nruab nrab cov cab kuj matrix uas tsis muaj cov ntxhiab tsw qab haus luam yeeb los yog tawm - ntawv.
Kev xa khoom cua txias:Tam sim ntawd sub- lus thiab rov qab- palate txias profile yam tsis muaj qhov iab txuam nrog crude menthol crystallization.
Kev ruaj ntseg:Inert formulation matrix kuaj los tiv thaiv esterification los yog tsw sib cais thaum lub sij hawm ceev aging xeem.
Ntim
Ntim Hom:Khoom noj khoom haus- qib siab- ntom polyethylene (HDPE) carboys, fluorinated HDPE nruas, thiab 316L stainless hlau siab hlab ntsha.
Qhov ntau thiab tsawg muaj:1 kg, 5 kg, 25 kg, thiab 200 kg industrial configurations.
Kev ruaj ntseg foob:Induction- kaw, tamper- pom cov kaus mom nrog inert PTFE liners; nitrogen-flushed headspace thov kom tshem tawm cov pa oxygen ua ntej qhib.
Kev Tswj Xyuas Zoo
Analytical Verification:Txhua pawg tsim khoom raug kuaj los ntawm Shimadzu High-Performance Liquid Chromatography (HPLC) rau qhov tseeb nicotine assay thiab Gas Chromatography-Mass Spectrometry (GC- MS) rau kev tshuaj ntsuam xyuas impurity tsis haum.
Heavy Hlau Screening:Inductively Coupled Plasma Mass Spectrometry (ICP-MS) lees paub cov hlau lead, arsenic, cadmium, thiab mercury yog khaws cia qis dua 0.1 ppm kev txwv.
Kev tsim khoom ib puag ncig:Ua ke nyob rau hauv ISO 7 (Class 10,000) cov chaw huv huv uas siv kaw - voj HEPA huab cua pom thiab cov tshuab ntim ntim ntim tshuab.
Kev xeem & Cov ntaub ntawv
Cov khoom xa tuaj ntau:Certificate of Analysis (CoA) muab rau txhua tus neeg ntau lawm.
Cov ntaub ntawv kev nyab xeeb:Ntiaj teb no Harmonized System (GHS) raws li cov ntaub ntawv kev nyab xeeb (SDS) muab nrog thawj zaug xaj.
Traceability:Laser-etched ntau tus cim ntawm txhua lub thawv hla-cov ntaub ntawv raw khoom siv, cov ntaub ntawv sib xyaw ua ke, thiab chromatogram archives.
OEM / Private Label
Formulation Tailoring:Kev hloov kho rau qhov tshwj xeeb coil resistances (piv txwv li, 0.8-ohm mesh vs. 1.2-ohm ceramic) thiab tsom caj pas-ntaus siv nkhaus.
Production Scaling:Batch qhov ntau thiab tsawg scalable los ntawm 50 kg pilot khiav mus rau 5,000 kg industrial tso zis nyob rau hauv tus txheej txheem tsim txhuas lub sij hawm.
Regulatory Dossiers:Muab cov ntaub ntawv sib xyaw ua ke los txhawb cov neeg siv khoom sau npe cov ntaub ntawv.
Ua raws
Cov Qauv Zoo:Tsim nyob rau hauv ISO 9001 thiab tam sim no Kev Tsim Khoom Zoo (cGMP) cov txheej txheem rau kev sib xyaw tshuaj.
Raw Material Compliance:Tag nrho cov nicotine inputs ua raws li United States Pharmacopeia (USP) los yog European Pharmacopoeia (Ph. Eur.) specifications.
Kev txwv kev lag luam:Muab khoom tshwj xeeb raws li B2B kev tsim tawm tswv yim rau cov chaw lag luam uas tuav cov kev tsim khoom siv tau thiab cov ntawv tso cai luam yeeb / nicotine hauv lawv txoj haujlwm.
Cia
Qhov kub thiab txias:15-25 ° F (59 ° F txog 77 ° F). Tiv thaiv los ntawm khov thiab kub tshaj 30 degree.
Kev Tiv Thaiv Lub Teeb:Khaws rau hauv cov thawv opaque qub kom deb ntawm qhov raug UV ncaj qha los cuam tshuam cov duab -oxidation.
Lub neej txee:12 lub hlis txij li hnub tsim khoom nyob rau hauv qhov tsis tau qhib, thawj cov thawv ntim khoom khaws cia raws li kev pom zoo.
Cov lus nug nquag
Q: Dab tsi yog qhov tsawg kawg nkaus txiav txim kom muaj nuj nqis (MOQ) rau kev cai nicotine ntsev thiab tus neeg sawv cev txias formulations?
A: Tus qauv MOQ rau kev cai PG / VG piv, tsis yog - tus qauv nicotine lub zog, los yog tailored cooling agent concentrations yog 25 kg ib batch. Qhov ntim no ua kom muaj qhov sib xws thaum lub sijhawm ua haujlwm siab - shear mixing thiab muab cov qauv loj txaus rau kev txheeb xyuas HPLC.
Q: Yuav ua li cas batch-rau-batch sib xws nyob rau hauv caj pas thiab txias zog tswj?
A: Viscosity, ntom, thiab active ingredient concentrations yog tswj los ntawm automated gravimetric dosing systems backed los ntawm tiag -lub sij hawm HPLC assay verification. Batches raug tso tawm tsuas yog thaum cov txiaj ntsig kev tshuaj ntsuam poob qis hauv qhov nruj +/- 2% qhov siab ntev ntawm qhov sib piv rau tus tswv specification.
Q: Cov ntaub ntawv thev naus laus zis twg nrog rau txhua qhov khoom xa tuaj rau kev tswj xyuas cov ntaub ntawv txhawb nqa?
A: Txhua qhov kev xa khoom suav nrog ntau ntau - Daim Ntawv Pov Thawj Kev Ntsuam Xyuas (CoA), tag nrho HPLC thiab GC chromatograms, cov ntawv ceeb toom ntawm cov hlau hnyav ntawm ICP-MS, thiab GHS- raws li Daim Ntawv Qhia Kev Nyab Xeeb (SDS). Cov ntaub ntawv toxicological ntxiv cov ntsiab lus muaj nyob rau hauv kev sib koom ua ke tsis yog- daim ntawv cog lus tshaj tawm.
Q: Puas yog cov thawv ntim khoom sib xws nrog cov khoom siv ua kua puv tshuab
A: Yog. Cov khoom yog muab rau hauv cov zaub mov-qib, siab- ntom polyethylene (HDPE) los yog fluorinated nruas tau tshaj tus qauv peristaltic, piston- twj tso kua mis, thiab lub ntiajteb txawj nqus- pub automated filling machinery. Cov thawv ntim khoom yuav tsum nyob twj ywm thiab khaws cia ntawm 15℃thiab 25℃ua ntej kev koom ua ke rau hauv kab.
Q: Yuav ua li cas nicotine degradation thiab discoloration tiv thaiv thaum lub sij hawm kev thauj mus los thoob ntiaj teb?
A: Lub taub hau ntawm txhua lub thawv yog purged nrog kev kho mob -qib nitrogen roj ua ntej induction sealing. Qhov no tshem tawm cov pa oxygen seem, tiv thaiv oxidation, xim darkening, thiab tsim cov degradation byproducts xws li cotinine thaum dej hiav txwv los yog huab cua shipping.
Q: Dab tsi yog lub sij hawm txhuas txhuas rau cov khoom catalog qauv piv rau cov qauv kev cai?
A: Standard catalog formulations (xws li 20mg los yog 50mg standard ntsev bases nrog baseline txias profiles) nkoj nyob rau hauv 3 mus rau 5 hnub ua hauj lwm los ntawm Tshuag. Cov qauv kev cai xav tau kev txheeb xyuas qhov tseeb ntawm qhov tsis yog - cov qauv tshwj xeeb feem ntau xav tau 10 mus rau 15 hnub ua haujlwm txij li kev pom zoo rau kev tso tawm QA zaum kawg.
Cim npe nrov: txias nicotine ntsev e-kua, Tuam Tshoj txias nicotine ntsev e-kua lwm tus neeg
